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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HMCN1
All Species:
16.97
Human Site:
S2680
Identified Species:
53.33
UniProt:
Q96RW7
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96RW7
NP_114141.2
5635
613390
S2680
D
L
W
G
P
G
L
S
P
K
E
V
K
I
K
Chimpanzee
Pan troglodytes
XP_514061
5635
613367
S2680
D
L
W
G
P
G
L
S
P
K
E
V
K
I
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547438
5637
613232
S2682
D
L
L
G
P
G
L
S
P
K
E
V
K
I
K
Cat
Felis silvestris
Mouse
Mus musculus
NP_001019891
5634
611543
S2679
D
L
L
G
P
G
L
S
P
K
E
V
K
I
R
Rat
Rattus norvegicus
XP_001070255
5635
611553
S2680
D
L
L
G
T
G
L
S
P
K
E
V
K
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920501
4211
454872
V1387
P
V
L
E
T
P
G
V
Y
L
Q
N
G
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001024582
5198
570803
Q2374
N
S
A
G
S
V
E
Q
D
V
N
V
N
V
I
Sea Urchin
Strong. purpuratus
XP_780140
3664
401987
R840
K
G
D
R
D
L
T
R
V
T
Y
T
R
I
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
N.A.
91.1
N.A.
87.3
87
N.A.
N.A.
N.A.
N.A.
36.1
N.A.
N.A.
N.A.
28.3
23.4
Protein Similarity:
100
99.5
N.A.
95.1
N.A.
93.4
93.5
N.A.
N.A.
N.A.
N.A.
50.9
N.A.
N.A.
N.A.
44.8
36.7
P-Site Identity:
100
100
N.A.
93.3
N.A.
86.6
80
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
86.6
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
63
0
13
0
13
0
0
0
13
0
0
0
0
0
0
% D
% Glu:
0
0
0
13
0
0
13
0
0
0
63
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
13
0
75
0
63
13
0
0
0
0
0
13
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
75
13
% I
% Lys:
13
0
0
0
0
0
0
0
0
63
0
0
63
13
38
% K
% Leu:
0
63
50
0
0
13
63
0
0
13
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
0
0
0
0
0
0
0
0
0
13
13
13
0
0
% N
% Pro:
13
0
0
0
50
13
0
0
63
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
13
0
0
13
0
0
0
0
% Q
% Arg:
0
0
0
13
0
0
0
13
0
0
0
0
13
0
38
% R
% Ser:
0
13
0
0
13
0
0
63
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
25
0
13
0
0
13
0
13
0
0
0
% T
% Val:
0
13
0
0
0
13
0
13
13
13
0
75
0
13
0
% V
% Trp:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
13
% W
% Tyr:
0
0
0
0
0
0
0
0
13
0
13
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _